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  • Okay I've never bothered to look into any of this, but why is it antioxidants are so important? Don't I want oxygen? Google is just giving mlm, Reddit and ai slop answers

    • So your body naturally creates certain oxygen containing molecules called free radicals. These are created in response to stress, immune response, and environmental stressors like UV light, radiation, and smoke. Free radicals are highly reactive as they lack a valence electron. Due to this reactivity they can damage molecules that make up your cells, including DNA, and lead to long term health issues. This is called oxidative stress. Antioxidants are molecules which have an extra electron and readily donate it to molecules that are lacking one, in this case the free radicals in your body. Their importance is in this function of reducing oxidative stress.

    • I don't remember why, but certain compounds break down into "free radicals", or single oxygen atoms (as opposed to double-bonded oxygen molecules) that very easily bond to other compounds in your body and break them down.

      Antioxidants cut down on the free radicals in your blood (typically by bonding with them first, I believe) to prevent them from destroying important compounds in your body.

  • Methylene blue may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs.

    https://www.ncbi.nlm.nih.gov/books/NBK557593/ Methylene blue is a medication used in the management and treatment of methemoglobinemia, a condition in which hemoglobin decreases its ability to carry oxygen. This activity reviews the indications, action, adverse effects, and contraindications for methylene blue as a valuable agent in the therapy of methemoglobinemia, vasoplegic syndrome, Plasmodium falciparum, and ifosfamide-induced encephalopathy, as well as for diagnostic purposes such as sentinel lymph node mapping during breast procedures and parathyroid gland mapping during parathyroidectomies. This activity will highlight the indications, mechanism of action, adverse event profile, and other key factors pertinent for members of a healthcare team managing patients with methemoglobinemia and related conditions.

    Methylene blue has FDA approval for the treatment of methemoglobinemia, a condition when Fe2+ of hemoglobin gets oxidized to Fe3+, reducing the oxygen-carrying capacity of hemoglobin, and typically presents with cyanosis of the lips and extremities, characteristic "chocolate-colored urine," and hypoxia.[1] Methemoglobinemia results from exposure to certain drugs such as dapsone, a drug indicated for the treatment of Mycoplasma leprae and Pneumocystis jirovecii prophylaxis, benzocaine (a local anesthetic), high altitude water sources, and nitrites such as nitroglycerin or amyl nitrite used for treating coronary artery disease.[

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