Do not resist

I don't really struggle with hay fever but it hit me hard on a trip to Japan

Allergies are proof that intelligent design is bullshit.
- Added to the infinite list.
  
  que the I'm a banana video
  hehe spoon
  *the idiot who posted this forgot the ue
- Also the vagus nerve.
  
  That fucking trash. I’ve got vasovagal syncope.
  A sudden drop in heart rate and blood pressure leading to fainting, often in reaction to a stressful trigger.
  Common triggers include strain, stress, long periods of standing, heat exposure, or the sight of blood.
  Symptoms include paleness, nausea, sweating, a rapid heartbeat, and fainting.
  It’s inconsistent, though. For example, never had issues with the numbing shots at the dentist. One day they start giving the shots to numb me up, and next thing I remember they’ve got me sitting up over a trash can trying to clear the vomit I was aspirating on. Scared the shit out of those dentists.
  Once while in middle school I lightly nicked a finger with some scissors - barely even bled. All of a sudden I feel nauseous and ask to go to the bathroom. I manage to get out into the hallway before collapsing to the floor, hitting my head at least twice on the way down and traumatizing my classmates who thought I just dropped dead.
  Intelligent design my big gay ass. Damn vagus nerve is a dodgy self-destruct mechanism.
  
  Also paranasal sinuses.
- I mean don't they also say it was "god's plan" when a 6 year old dies of cancer? There is no point in trying to argue with zealots.

*Histamines. Antibodies are far less disruptive. Histamines protect us from larger invaders like worms and other parasites. Antihistamines antagonize histamines at receptor sites, preventing the itchy, red, swelling reaction we associate with an allergen.
- Acktually – IgE(/antibodies) are bound to the surface of mast cells. Antigens/allergens bind to the IgE receptor and actives the mast cell, releasing histamines. Allergy can actually be treated with anti-IgE (monoclonal) antibodies (Omalizumab)!
  
  Thank you for the detail! I just repeated the dumbed-down explanation given to me by my allergist.
- Are you sure histamines are larger than antibodies?
  That's 17 atoms if I can count correctly.
  Antibodies are made of proteins and should therefore be much larger.
  
  I just confirmed. They’re only 17 atoms in size. My memory failed me. I edited the comment. Thanks for the correction!

"Welcome. You will experience a tingling sensation and then death."

FREAK OUT ACTIVATED
is more like it

While my body is like: ah sure, come on in, nobody cares. I guess the allergens just leave for greener pastures.

Reading this as my body went fucking nuclear on me the moment my allergy meds wore off and I was a fucking tears and snot fountain at 1am until I took a Zyrtec until it chilled by 2. Even then, I still have fucking drop going on in the back of my throat... ugh...

Anyone have experience with the shots you can get to mitigate allergies/immunotherapy? I was thinking about getting them to temper my chronic sinusitis, and I don’t want to take Claritin for life.
- I took them for a few years in middle/high school, and they worked well for me. If you don’t feel like going to a doctor every week for the shots (and you aren’t too freaked out by needles) you can usually also administer them yourself. My roommate in high school hated needles and shots, so I’d of course make sure to administer the shots while he was in the room.
  
  My spouse administers their own shots for their Chron's disease medication; are the shots pretty much like... the tubular thingies wherein the needle's kinda hidden and all you feel is the prick after pressing a button? Or is it like... the full-on here's-a-fucking-needle-good-luck-chump shot?
  
  Is it still expensive if you do the injections yourself?
- They can be effective. But speak with your doc first. I found them rather tedious as a kid
- Not me, but my friend recently got approved for Dupixent and although he hates that he needs to even do this he says it's night and day from before. Basically lived his entire life with not being able to breath. He got surgery, and it helped for a bit, but over time it came back. He says just being able to breathe normal is worth it.
- Currently in my (I think) 4th year out of 5. I took them because I kept getting adenoid infections and wanted to avoid two surgeries. Has been a major improvement, but I still have to take an allergy pill every day and the occasional nasal spray. Hadn’t had another infection since year 1. You have to get shots every 3-7 days for several months and then they slowly spread it out over time. I’m once a month now. If you don’t have insurance it’s very expensive, especially the first year.

Thanks for the reminder to take my allergy meds!

Happy Spring!

it's almost that time of the year again