Even if you think most drugs are being imported from Mexico (they are not, but we can talk about that later). Do you really think a tariff is going to affect the drug market?
Do you think some guy on border patrol is looking at all the cocaine in a basin and saying "yeah man I'm gonna have to charge you 25% more for this."
Hope everyone in the US enjoys a 25% mark up on paper, lumber, water, oil and gas, uranium.... pretty sure there's more stuff coming down from Canada, but that's top of my head.