just reading off their site: Prerequisites
A hackable Nintendo Switch console (preferably a model that is vulnerable to the fusée-gelée exploit).
Visit Is My Switch Patched? to check if your console is not patched.
A microSD card with at least 32 GB of storage capacity. 64 GB or higher is recommended.
A USB-C to USB-A or USB-C to USB-C cable to connect your Switch to your computer.
TegraRcmGUI – Download TegraRcmGUI_v2.6_Installer.msi
ums-loader – Download ums-loader.bin
Hekate – Download hekate_ctcaer_X.X.X_Nyx_X.X.X.zip
Windows users: Also download nyx_usb_max_rate__run_only_once_per_windows_pc.reg and run it for faster transfer speeds over USB. For details, see the NOTE section in the release page.
This hekate configuration file – hekate_ipl.ini
Atmosphére – Download both atmosphere-X.X.X-master-XXXXXXXX+hbl-X.X.X+hbmenu-X.X.X.zip and fusee.bin.
Lockpick_RCM – Download Lockpick_RCM.bin
NXDumpTool – Download nxdumptool.nro
nxDumpFuse – Download win-x64.zip
TegraExplorer – Download TegraExplorer.bin
(Optional) JKSV – Download JKSV.nro
Download this homebrew application if you wish to dump your save data from your Switch to yuzu.
RCM Jig – We highly recommend one like this, but you could use any of the methods outlined here.
You definitely can! I'm using Yuzu on Linux with an jurassic 1050Ti and it works perfectly. I basically play Mario Kart 8 and BotW (for now, TotK in the queue) and never touched an actual Switch in person (seriously! I'm Brazilian and these things are hell expensive here).