Well, Plex is a media server 1st and foremost. I've never heard of Infuse before, so I did a search and from what I read it is just an iOS media player that can pull from multiple servers (including Plex.) So, I use Plex to manage all of my media and they have native apps for pretty much everywhere including smart TV's, Andriod, iPhone, Windows, Linux, Mac, gaming systems, and a web player. I am currently looking into FOSS alternatives, but for the past 10 years Plex has been the best for my needs.