The irony is that the comments that got me the most karma weren't the ones I considered of highest value. A detailed, genuinely helpful response in a small subreddit might only garner a half-dozen upvotes while a snarky one-liner in a big sub can boost karma by thousands.
I wrote a comment about how to fix a rare bug on a specific drone, not even fixed by the manufacturer. Each person clicking my link saved hundreds of dollars. It got me less maybe 10 upvotes but fixed thousands of dollars of equipment.