Fallout New Vegas (pure vanilla with not a single mod aka the console editions and the broken PC ports).
It's sometimes hard to recommend FNV to other people due to the fact that the only way to really enjoy the game is using the Viva New Vegas modlist.
I'm never reinstalling Windows so I have to pray that MO2 gets ported to Linux sooner rather than later because I personally despise hacking with WINE prefixes/organizing esps/ESM files myself. Also the fact that
Mods are distributed through a proprietary network shithole service called Nexus Mods
I own a copy of the game on Steam unfortunately and I know how much I despise interfacing with that program.
I'd highly recommend it - pretty much one click for a lot of annoying things with compatibility. If you run out of Flatpaks it's a bit of extra leg work but still pretty simple.
For what it's worth, that script worked for me perfectly out of the box a couple months ago on Debian. This was after spending many hours trying and failing to get MO2 or Vortex running through Protontricks, Steam Tinker Launch, and Lutris.
I used an older version for Skyrim on Fedora, just had to rename main.exe to whatever launcher exe steam uses to launch the game and replace the original