Hydroxychloroquine could have caused almost 17,000 deaths in six countries during COVID, study finds
Hydroxychloroquine could have caused almost 17,000 deaths in six countries during COVID, study finds
Former US President Donald Trump said: ‘What do you have to lose? Take it.’
Oh wtf this was one of the drugs people used to poison themselves with? I was prescribed this a month ago because the rheumatologist told me is the safest drug for auto immune issues although I still need to take mehtylprednisolone every few months due to spinal inflammation that messes with nerves.
Don't worry, a key part of toxicity is the dosage. If you're following a prescription from an actual doctor instead of taking handfuls of horse medication at the behest of extremist politicians you're fine.
I followed my doctors advice (400mg daily for 15 years) and got retinol toxicity anyway. Now I have permanent damage to my macular, can’t take hydroxychloroquine anymore and my lupus is raging. It’s a fantastic drug, and blindness is a very very rare side effect, but for god’s sake insist on being monitored by an ophthalmologist. Current UK recommendations are an eye check before starting the medication, repeated after 5 years and then every year after that. I should have been checked 10 times in 15 years, I was checked twice.
Ivermectin was the horse medication.
It's great if it's used to treat what it was meant to, people started taking it because a few doctors mentioned it might help with COVID without having any proof it did.
People were self dosing with it from OTC veterinary medication meant for horses. Important to point that out b/c there was nothing wrong with experienced doctors exploring every option.
The hazards here were related to passing around doses, improper prescriptions from disreputable doctors, and not seeking out actual treatments for covid. If you have certain conditions and medications there can be side effects and interactions that harm health, but that your doctor should have considered. Some people who really needed hydroxychloroquine for legitimate uses like yours had trouble getting it because of shortages due to morons rushing out to get it.
Also, let's not forget about the people taking stuff they got from pet stores. Stuff meant for pouring into fish tanks, or doses literally meant for horses.
Just like Ivermectin, it has a legitimate use. But snakeoil salesmen peddled both of them as off label Covid miracle cures with zero medical trials, or even an attempt to begin one.
Ivermectin is for deworming. It shouldn't be prescribed outside of the purpose.
Take the recommended dose and you'll be fine, just don't go over because it's easy to OD with.
You might also go blind, but that's a future you problem
If you take a look at the more dangerous collateral effects... and correlate with the more dangerous COVID effects, you'll have a surprise.
By itself, the drug is pretty safe.
Remember these chuckleheads believe the vaccine is poison and you gotta be careful and they put this stuff into themselves. Apparently research is listening to Joe's podcast.
Anybody that takes medical advice from Joe Rogan deserves whatever malady or health problem they get. Literal leopardsatemyface…
"What do you have to lose?"
Umm. Their lives, apparently? Such an irresponsible statement.
Natural Selection
Generally yes, but there's cases where parents gave this shit to their kids too.
Technically, that still serves to remove their genes from the pool.
That's technically also natural selection.
Maybe you should think twice before posting this kind of uncompassionate drivel.
Some of these people died because they trusted the prescription from their doctor. Not everybody is able to read and understand scientific literature, and they might have to rely on the authority of someone they trust. Some doctors believed, against all evidence, that this was the right thing to prescribe and some patients took their word for it.
That figure stems from a study published in the Nature scientific journal in 2021 which reported an 11 percent increase in the mortality rate, linked to its prescription against COVID-19, because of the potential adverse effects like heart rhythm disorders, and its use instead of other effective treatments.
So I think what they are reporting is an estimate of people who died of COVID whilst taking this stuff and so did not undertake other forms of treatment.
I don't think they are saying that most of these people died as a direct result of taking the drug. (e.g. overdosing)., despite what the headline suggests.
Not quite. The drug causes heart irregularities in some people at therapeutic doses, and this killed some of those 17k people. It just doesn't quantify it here.
The study does quantify the cardiac risk from HCQ. Those causes of death are included in the all-causes mortality rate previously determined by a separate meta analysis
If you read the original study, those causes are included.
The amount of people not reading the article or the study is astounding.
This is not about Trump.
This is not about your conservative uncle.
This is not about America only.This is about off label prescribing in ICU and ERs early in the pandemic with low evidence (theoretical pathways) in six countries which either gave explicit approval or unclear guidance that was interpreted as approval. It goes on to suggest that in a similar emergency future, the state agencies sould do better.
In the absence of restriction, the number of expected HCQ-related deaths is likely to be directly related to the promotion of its prescription by scientists, physicians and health agencies. In February and March 2020, the use of this treatment was widely promoted based on preliminary reports suggesting a potential efficacy against COVID-19 [80]. For instance, the use of HCQ markedly increased from mid-March to mid-April 2020 [81], [82] in France before a temporary recommendation supporting its use by the State Council was rapidly rejected [83]. Similarly, the Food and Drug Administration (FDA) granted a temporary emergency use authorisation for HCQ on March 28th 2020, which was finally revoked on June 15th 2020 [84]. In India, HCQ was also prescribed as a curative treatment to patients with COVID-19 and as a prophylactic treatment for front-line workers based on public authority guidance [85]. Conversely, the British government promoted HCQ use only within clinical trials, explaining the absence of cohort studies reporting the use of HCQ in the United Kingdom in the present study [86]. Consistently, a cohort of a multinational network showed a wide variation in the use of HCQ between countries, with 85% in Spain, 14% in the USA and less than 2% in China [80]. The rush to administer this treatment caused supply shortages in community pharmacies, forcing the implementation of dispensing restrictions [82]. Finally, the results of observational studies and randomized trials in May and June 2020, respectively, convincingly demonstrated that HCQ was ineffective and led to an increase in adverse events [4], [5], [12], [66], [73].
This is the main point : the breach of the trust we could have in state agencies and doctors. Hopefully the lesson stick this time.
But I'm not allowed to add caffeine powder to my yogurt anymore because one idiot died 🙄
Stupid is as stupid does.
Former US President Donald Trump said: ‘What do you have to lose? Take it.’
As a proud and patriotic French, I can't let the murican brag about their (former) President without bragging about our former and current President whom happen to be a very good epidemiologist :
Today his profile rose even higher, as French President Emmanuel Macron traveled to Marseille to meet Raoult, a hospital director and researcher who led the two trials. Macron did not comment after the meeting, but the rendezvous, initiated by Macron, was a clear sign of Raoult's newfound political clout. Jean-Paul Hamon, president of the Federation of Doctors of France, one of many scientists and doctors critical of the meeting, called it "showbiz politics."
A survey released by French polling institute IFOP on 6 April revealed that 59% of the French population believes chloroquine is effective against the new coronavirus. Confidence in the drugs is higher on the far right and far left, and reached 80% among sympathizers of the "yellow vest" movement that staged massive protests against Macron's economic policy in 2018 and 2019. Support is also very high, at 74%, in the Marseille region.
Karine Lacombe, head of infectious diseases at the Saint Antoine Hospital in Paris, has said on French TV that she and her team have received repeated "physical threats" for refusing to prescribe chloroquine; she said she has also seen many falsified prescriptions for the drug. Other doctors have reported similar experiences. The pressure comes on top of the stress caused by shortages of protective equipment, diagnostic tests, and medical staff.
Here is an alternative Piped link(s):
Piped is a privacy-respecting open-source alternative frontend to YouTube.
I'm open-source; check me out at GitHub.
Macron is an excellent epidemiologist, he read a lot about it....
That's more then all Vaccines COMBINED! Don't let our Kids get Vaxxed! Hydrochloroquine them instead!
Reminds me of the parents who left their baby with the grandparents and the grandparents gave the baby ivermectin to 'protect' them from COVID.
Hospital couldn't save the poor kid.
Donald Trump should be charged for those deaths. Sadly, it is unlikely that the families that took his advice would take out a class action. As to his comment about what have you got to lose? The court or any reasonable party simply has to read the patient information leaflet.
Donald Trump should be charged for those deaths.
To be fair, it's not entirely his fault that those individuals made poor choices. Yet, his actions were pretty awful, especially considering that those who passed away probably supported him by voting
It's always an interesting discussion when we raise the question of:
If people who are born with disabilities and intellectual impairments get special treatment, what is the threshold for being so stupid that you can't be considered responsible for your actions (or be expected not to be manipulated or misled)?
There is a strong argument that people who aren't that smart can't really be held accountable for their actions, as its beyond their control.
I’m going to be that guy to say… The world is better off from it.
Nah, if it was only the stupid doing it to themselves that would be fine, but as someone on the medical field, you have no idea of how many cases I saw of little kids and elderly patients who were fed those pills by their loved ones.
It's astonishing how much aoe dmg stupidity does.
One of my relatives did the same when I tested positive, even writing an rx for me and really pushing it. Never took any and this story makes me even more glad I didn’t listen to the facebook research
Many good people aren't that savvy in all fields and have a peer pressure to try this and that, especially when disinformation is louder than truth. They can have good reasons like not making their fragile elderly ill, and there's a gossiped ultimate cure to that. Can you blame them they choose it? They are a small part of that problem under the towering issue of grifters, fakes, conspiracies running amok.
I have nothing against a person facing almost certain death throwing everything at a problem. If someone would throw me off a cliff I would spend my last few moments trying to learn how to fly while offering prayers to every god I can think of. What I have problem with is people who don't do what they are supposed to do.
I pity the children that died from this nonsense. As for the other ones, not so much.
This is the best summary I could come up with:
Nearly 17,000 people may have died after taking hydroxycholoroquine during the first wave of COVID, according to a study by French researchers.
The anti-malaria drug was prescribed to some patients hospitalized with COVID-19 during the first wave of the pandemic, "despite the absence of evidence documenting its clinical benefits," the researchers point out in their paper, published in the February issue of Biomedicine & Pharmacotherapy.
Now, researchers have estimated that some 16,990 people in six countries — France, Belgium, Italy, Spain, Turkey and the U.S. — may have died as a result.
Researchers from universities in Lyon, France, and Québec, Canada, used that figure to analyze hospitalization data for COVID in each of the six countries, exposure to hydroxychloroquine and the increase in the relative risk of death linked to the drug.
In fact, they say the figure may be far higher given the study only concerns six countries from March to July 2020, when the drug was prescribed much more widely.
Hydroxychloroquine gained prominence partly due to French virologist Didier Raoult who had headed the Méditerranée Infection Foundation hospital, but was later removed amid growing controversy.
The original article contains 260 words, the summary contains 187 words. Saved 28%. I'm a bot and I'm open source!
"COULD HAVE"
I'm so sick of this sort of reporting. Too many "maybe", "might have", "could be". it's just fear mongering.
'Could have' is due to the range of potential estimates. The confidence interval was between 6420–20294 deaths.
Lol, I love it when people get all worked up and it turns out they are upset for idiotic reasons.
and with some luck, they completely removed themselves from the gene pool
Ha!
So looks like my city will get some snow this weekend. That should be fun. The holidays kinda wiped me out and looking to hang around the house. What's new with you guys?