If they could just make it like the ⌘ command key on macOS it wouldn't be so bad, but of course, they're going to make it just like the goddamn Windows key, yet another key that if you press, it will screw up your workflow and have some dumb pop-up thing come up. Another modifier key wouldn't be so bad (or just turning the Windows key into a modifier key that doesn't automatically pull up a dumb menu if accidentally pressed by itself). They really like beating people over the head with their useless features.
You can "disable" keys using an app like AutoIt or AutoHotKey to capture the input and just do nothing with it. Takes a 3 line script.
I've done this for years with my left Windows key, for playing games. I also add the left Alt-Tab when playing certain games, so I don't accidentally tab out.
If you're into custom keyboards you can also configure the entire PCB using things like QMK so any key can be anything you want. It is a significantly more expensive route the AHK though.