How the motion of DNA controls gene activity
How the motion of DNA controls gene activity
Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A group of scientists now visualized this dynamic process and give novel insights into the physical c...
Using florescent markers, the researchers are able to track pairs of DNA loci in 3D, showing the interaction between distantly spaced parts of the genome. Implications in gene expression as enhancers and promoters for genes may be very far away from said gene.
Paper: https://www.science.org/doi/10.1126/science.adf5568
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