Most drugs should be over-the-counter. The especially dangerous or addictive ones maybe just require counselling with a pharmacist first. But I'm more concerned about people not able to access the medication they need than I am about idiots removing themselves from the gene pool by OD.
People in my dumbass country would rather 10 people with a genuine medical need suffer as long as 1 addict can't get a fix, and it's so many layers of bullshit.
there's not really a way to know for sure but I imagine the price would actually come down somewhat due to removal of red tape and paperwork associated with drug control
possibly also from increased competition if that made it easier for a drug manufacturer to begin producing previously controlled drugs
for example amphetamine salt production is capped by the US DEA. if that cap were removed the supply would increase and the price might very well decrease