Do you roll with failures or do you load and try for your "expected" outcome?
I used to always try for the best outcome but with this have it seems like half of the time a failure also leads to an amazing consequence and story.
Like this from act one in the Underdark:
spoiler
I had to find a hidden gnome that could supply me with gunpowder, but she was so much on edge that she lit up the barrel of gunpowder and blew up the whole room, leaving half of my party dead. A suicide gnome bomber. I couldn't convince her that I was not an enemy. Reloaded just to see if I could successfully do it, but much preferred the first outcome of the dice roll, so had to reload and try 6 times until I failed again. What a game!
I tend to only reload when something buggy or unintended happens(misclick) or if it's a really risky/story related thing I feel my character would be good at but got a nat 1.
But this has been one of the few games I've totally rolled with most of my dialogue/skill failures just because they still feel decent narratively. I'll save finding out what the successful/alternate outcomes are for next playthrough!