I was experimenting with the Cadence tools from KXStudio. These are mostly made for JACK, but PipeWire has a JACK interface so it should work. It's similar to helvum, but with more options.
Not sure right now which one (maybe Carla), but one of these programs also support adding sound effect nodes that have their own GUI! You probably want to use it in multi-client or patchbay mode
My audio set up is using jack on Ubuntu. If I were to start using pipewire, does it replace jack? Or do you use it alongside jack?
I use mostly ardour, hydrogen, renoise and bitwig.
qjackctl will actually connect to pipewire, I use its graph window a lot to route audio when the default volume control isn't enough. But yeah it does (or can) replace jackd.