I don't have adblock on my work computer. I don't want it interfering with webdev and I've found it to do so in the past. But it's interesting, the dichotomy between sites I use as development resources vs the rest of the web. My phone and home computer are unbearable without adblock, but on my work computer, the ads are hardly noticeable really.
Its ultimately based on the sites you frequent at work vs home. The sites i read stuff at work tend to be less in your face with ads,.so you know its there but theyre less distracting.